Horiba - OpenPlex Binding Analysis2013-05-07
Real time binding analysis made easy with OpenPlex
HORIBA Scientific is pleased to announce the launch of OpenPlex, a flexible research platform for the real time analysis of label-free molecular interactions in a multiplex format.
OpenPlex uses Surface Plasmon Resonance imaging (SPRi) to monitor the binding of molecules to an array of receptors immobilized on a sensor chip. It can give qualitative (Yes/No binding) and quantitative information of the interactions such as concentration, affinity (KD), association and dissociation rates (kon, koff). Molecular interactions involving proteins, DNA, RNA, oligosaccharides, living cells, polymers or nanoparticules can be characterized and quantified.
OpenPlex is the evolution of SPRi-Lab+, the bench-top flexible label-free instrument from HORIBA Scientific. This instrument was designed for simple operation and is adapted to multiple applications covering physico-chemistry, biochemistry, biology and nanotechnology. Different flow cell configurations are available, making the combination of label-free molecular interaction analysis to fluorescence or electrochemistry even easier. This new design will facilitate cutting-edge research, from nanotechnologies to biomedical research.